Development of genetic and electrochemical diagnosis and inhibition technologies for invisible corrosion caused by microorganisms (Contract research); FY2022 Nuclear Energy Science & Technology and Human Resource Development Project

Collaborative Laboratories for Advanced Decommissioning Science; National Institute for Materials Science*

JAEA-Review 2023-031, 101 Pages, 2024/01

JAEA-Review-2023-031.pdf:24.47MB

The Collaborative Laboratories for Advanced Decommissioning Science (CLADS), Japan Atomic Energy Agency (JAEA), had been conducting the Nuclear Energy Science & Technology and Human Resource Development Project (hereafter referred to "the Project") in FY2022. The Project aims to contribute to solving problems in the nuclear energy field represented by the decommissioning of the Fukushima Daiichi Nuclear Power Station (1F), Tokyo Electric Power Company Holdings, Inc. (TEPCO). For this purpose, intelligence was collected from all over the world, and basic research and human resource development were promoted by closely integrating/collaborating knowledge and experiences in various fields beyond the barrier of conventional organizations and research fields. The sponsor of the Project was moved from the Ministry of Education, Culture, Sports, Science and Technology to JAEA since the newly adopted proposals in FY2018. On this occasion, JAEA constructed a new research system where JAEA-academia collaboration is reinforced and medium-to-long term research/development and human resource development contributing to the decommissioning are stably and consecutively implemented. Among the adopted proposals in FY2020, this report summarizes the research results of the "Development of genetic and electrochemical diagnosis and inhibition technologies for invisible corrosion caused by microorganisms" conducted from FY2020 to FY2022. The present study aims to develop innovative diagnostic techniques such as accelerated test specimens and on-site genetic testing for microbially induced and accelerated corrosion of metallic materials (microbially influenced corrosion, MIC), and to identify the conditions that promote MIC at 1F for proposing methods to prevent MIC through water quality and environmental control.

The Effects of unburned-gas temperature and pressure on the unstable behavior of cellular-flame fronts generated by intrinsic instability in hydrogen-air lean premixed flames under adiabatic and non-adiabatic conditions; Numerical simulation based on the detailed chemical reaction model

Thwe Thwe, A.; Kadowaki, Satoshi; Nagaishi, Ryuji

Journal of Nuclear Science and Technology, 60(6), p.731 - 742, 2023/06

https://doi.org/10.1080/00223131.2022.2143448

In this study, we performed numerical calculations of unsteady reaction flow considering detailed chemical reactions, investigated the unstable behavior of hydrogen-air dilute premixed flame due to intrinsic instability, and clarified the effects of unburned gas temperature and pressure. I made it. The unstable behavior of the flame in a wide space was simulated, and the burning rate of the cellular flame was obtained. Then, the effects of heat loss and flame scale on flame unstable behavior were investigated. The burning velocity of a planar flame increases as the unburned-gas temperature increases and it decreases as the unburned-gas pressure and heat loss increase. The normalized burning velocity increases when the pressure increases and heat loss becomes large, and it decreases when the temperature increases. This is because the high unburned-gas pressure and heat loss promote the unstable behavior and instability of flame.

Implication of E3 ligase RAD18 in UV-induced mutagenesis in human induced pluripotent stem cells and neuronal progenitor cells

Shimada, Mikio*; Tokumiya, Takumi*; Miyake, Tomoko*; Tsukada, Kaima*; Kanzaki, Norie; Yanagihara, Hiromi*; Kobayashi, Junya*; Matsumoto, Yoshihisa*

Journal of Radiation Research (Internet), 64(2), p.345 - 351, 2023/03

https://doi.org/10.1093/jrr/rrac099

Development of genetic and electrochemical diagnosis and inhibition technologies for invisible corrosion caused by microorganisms (Contract Research); FY2021 Nuclear Energy Science & Technology and Human Resource Development Project

Collaborative Laboratories for Advanced Decommissioning Science; National Institute for Materials Science*

JAEA-Review 2022-045, 82 Pages, 2023/01

JAEA-Review-2022-045.pdf:4.6MB

The Collaborative Laboratories for Advanced Decommissioning Science (CLADS), Japan Atomic Energy Agency (JAEA), had been conducting the Nuclear Energy Science & Technology and Human Resource Development Project (hereafter referred to "the Project") in FY2021. The Project aims to contribute to solving problems in the nuclear energy field represented by the decommissioning of the Fukushima Daiichi Nuclear Power Station (1F), Tokyo Electric Power Company Holdings, Inc. (TEPCO). For this purpose, intelligence was collected from all over the world, and basic research and human resource development were promoted by closely integrating/collaborating knowledge and experiences in various fields beyond the barrier of conventional organizations and research fields. The sponsor of the Project was moved from the Ministry of Education, Culture, Sports, Science and Technology to JAEA since the newly adopted proposals in FY2018. On this occasion, JAEA constructed a new research system where JAEA-academia collaboration is reinforced and medium-to-long term research/development and human resource development contributing to the decommissioning are stably and consecutively implemented. Among the adopted proposals in FY2020, this report summarizes the research results of the "Development of genetic and electrochemical diagnosis and inhibition technologies for invisible corrosion caused by microorganisms" conducted in FY2021. The present study aims to develop innovative diagnostic techniques such as accelerated test specimens and on-site genetic testing for microbially induced and accelerated corrosion of metallic materials (microbially influenced corrosion, MIC), and to identify the conditions that promote MIC at 1F for proposing methods to prevent MIC through water quality and environmental control. We also aim to develop a research base based on materials, microorganisms, and electrochemistry, to develop technologies that can be used by engineers in the field, …

Simulation of the self-propagating hydrogen-air premixed flame in a closed-vessel by an open-source CFD code

Thwe Thwe, A.; Terada, Atsuhiko; Hino, Ryutaro; Nagaishi, Ryuji; Kadowaki, Satoshi

Journal of Nuclear Science and Technology, 59(5), p.573 - 579, 2022/05

https://doi.org/10.1080/00223131.2021.1990153

The simulations of the combustion of self-propagating hydrogen-air premixed flame are performed by an open-source CFD code. The flame propagation behavior, flame radius, temperature and pressure are analyzed by varying the initial laminar flame speed and grid size. When the initial laminar speed increases, the thermal expansion effects become strong which leads the increase of flame radius along with the increase of flame surface area, flame temperature and pressure. A new laminar flame speed model derived previously from the results of experiment is also introduced to the code and the obtained flame radii are compared with those from the experiments. The formation of cellular flame fronts is captured by simulation and the cell separation on the flame surface vividly appears when the gird resolution becomes sufficiently higher. The propagation behavior of cellular flame front and the flame radius obtained from the simulations have the reasonable agreement with the previous experiments.

Establishing a new evaluation system to characterize radiation carcinogenesis by stem cell dynamics (Contract research); FY2020 Nuclear Energy Science & Technology and Human Resource Development Project

Collaborative Laboratories for Advanced Decommissioning Science; National Institutes for Quantum Science and Technology*

JAEA-Review 2021-052, 52 Pages, 2022/01

JAEA-Review-2021-052.pdf:2.63MB

The Collaborative Laboratories for Advanced Decommissioning Science (CLADS), Japan Atomic Energy Agency (JAEA), had been conducting the Nuclear Energy Science & Technology and Human Resource Development Project (hereafter referred to "the Project") in FY2020. The Project aims to contribute to solving problems in the nuclear energy field represented by the decommissioning of the Fukushima Daiichi Nuclear Power Station, Tokyo Electric Power Company Holdings, Inc. (TEPCO). For this purpose, intelligence was collected from all over the world, and basic research and human resource development were promoted by closely integrating/collaborating knowledge and experiences in various fields beyond the barrier of conventional organizations and research fields. The sponsor of the Project was moved from the Ministry of Education, Culture, Sports, Science and Technology to JAEA since the newly adopted proposals in FY2018. On this occasion, JAEA constructed a new research system where JAEA-academia collaboration is reinforced and medium-to-long term research/development and human resource development contributing to the decommissioning are stably and consecutively implemented. Among the adopted proposals in FY2019, this report summarizes the research results of the "Establishing a new evaluation system to characterize radiation carcinogenesis by stem cell dynamics" conducted in FY2020. In this study, the long-term clonal expansion of mammary stem cells after high- to low-dose radiation exposure was investigated using stem-cell lineage tracing technology that can permanently label stem cells and their progenies. The purpose of this study is to characterize radiation-induced breast cancer based on the dynamics of radiation-exposed stem cells by capturing proliferation and analyzing it using a mathematical model.

Establishment of the measurement system of radiation dependent mutation in organ cells derived from human induced pluripotent stem cells (Contract research); FY2020 Nuclear Energy Science & Technology and Human Resource Development Project

Collaborative Laboratories for Advanced Decommissioning Science; Tokyo Institute of Technology*

JAEA-Review 2021-029, 64 Pages, 2021/12

JAEA-Review-2021-029.pdf:2.74MB

The Collaborative Laboratories for Advanced Decommissioning Science (CLADS), Japan Atomic Energy Agency (JAEA), had been conducting the Nuclear Energy Science & Technology and Human Resource Development Project (hereafter referred to "the Project") in FY2020. The Project aims to contribute to solving problems in the nuclear energy field represented by the decommissioning of the Fukushima Daiichi Nuclear Power Station, Tokyo Electric Power Company Holdings, Inc. (TEPCO). For this purpose, intelligence was collected from all over the world, and basic research and human resource development were promoted by closely integrating/collaborating knowledge and experiences in various fields beyond the barrier of conventional organizations and research fields. The sponsor of the Project was moved from the Ministry of Education, Culture, Sports, Science and Technology to JAEA since the newly adopted proposals in FY2018. On this occasion, JAEA constructed a new research system where JAEA-academia collaboration is reinforced and medium-to-long term research/development and human resource development contributing to the decommissioning are stably and consecutively implemented. Among the adopted proposals in FY2018, this report summarizes the research results of the "Establishment of the measurement system of radiation dependent mutation in organ cells derived from human induced pluripotent stem cells" conducted from FY2018 to 2020. Since the final year of this proposal was FY2020, the results for three fiscal years were summarized. The present study aimed to establish measurement system of radiation dependent mutation for analyze radiation effect to the human body. A distinctive feature of this study is to compare several organ cells which possess same genome DNA using human induced pluripotent stem cell. Further, using artificial intelligence technology and machine leaning method, we analyzed differences of mutation frequency during samples.

Mesh effect around burnable poison rod of cell model for HTTR fuel block

Fujimoto, Nozomu*; Fukuda, Kodai*; Honda, Yuki*; Tochio, Daisuke; Ho, H. Q.; Nagasumi, Satoru; Ishii, Toshiaki; Hamamoto, Shimpei; Nakano, Yumi*; Ishitsuka, Etsuo

JAEA-Technology 2021-008, 23 Pages, 2021/06

JAEA-Technology-2021-008.pdf:2.62MB

The effect of mesh division around the burnable poison rod on the burnup calculation of the HTTR core was investigated using the SRAC code system. As a result, the mesh division inside the burnable poison rod does not have a large effect on the burnup calculation, and the effective multiplication factor is closer to the measured value than the conventional calculation by dividing the graphite region around the burnable poison rod into a mesh. It became clear that the mesh division of the graphite region around the burnable poison rod is important for more appropriately evaluating the burnup behavior of the HTTR core..

Establishment of the measurement system of radiation dependent mutation in organ cells derived from human induced pluripotent cells (Contract research); FY2019 Nuclear Energy Science & Technology and Human Resource Development Project

Collaborative Laboratories for Advanced Decommissioning Science; Tokyo Institute of Technology*

JAEA-Review 2020-061, 56 Pages, 2021/01

JAEA-Review-2020-061.pdf:2.93MB

The Collaborative Laboratories for Advanced Decommissioning Science (CLADS), Japan Atomic Energy Agency (JAEA), had been conducting the Nuclear Energy Science & Technology and Human Resource Development Project (hereafter referred to "the Project") in FY2019. The Project aims to contribute to solving problems in the nuclear energy field represented by the decommissioning of the Fukushima Daiichi Nuclear Power Station, Tokyo Electric Power Company Holdings, Inc. (TEPCO). For this purpose, intelligence was collected from all over the world, and basic research and human resource development were promoted by closely integrating/collaborating knowledge and experiences in various fields beyond the barrier of conventional organizations and research fields. The sponsor of the Project was moved from the Ministry of Education, Culture, Sports, Science and Technology to JAEA since the newly adopted proposals in FY2018. On this occasion, JAEA constructed a new research system where JAEA-academia collaboration is reinforced and medium-to-long term research/development and human resource development contributing to the decommissioning are stably and consecutively implemented. Among the adopted proposals in FY2018, this report summarizes the research results of the "Establishment of the measurement system of radiation dependent mutation in organ cells derived from human induced pluripotent cells" conducted in FY2019. In this study, we aimed to establish measurement system of radiation dependent mutation for analyze radiation effect to the human body. A distinctive feature of this study is to compare several organ cells which possess same genome DNA using human induced pluripotent stem cell. Further, using artificial intelligence technology and machine leaning method, we will analyze differences of mutation frequency during samples.

Effects of pressure and heat loss on the unstable motion of cellular-flame fronts caused by intrinsic instability in hydrogen-air lean premixed flames

Kadowaki, Satoshi; Thwe Thwe, A.; Furuyama, Taisei*; Kawata, Kazumasa*; Katsumi, Toshiyuki; Kobayashi, Hideaki*

Journal of Thermal Science and Technology (Internet), 16(2), p.20-00491_1 - 20-00491_12, 2021/00

https://doi.org/10.1299/jtst.2021jtst0021

Effects of pressure and heat loss on the unstable motion of cellular-flame fronts in hydrogen-air lean premixed flames were numerically investigated. The reaction mechanism for hydrogen-oxygen combustion was modeled with seventeen reversible reactions of eight reactive species and a diluent. Two-dimensional unsteady reactive flow was treated, and the compressibility, viscosity, heat conduction, molecular diffusion and heat loss were taken into account. As the pressure became higher, the maximum growth rate increased and the unstable range widened. These were due mainly to the decrease of flame thickness. The burning velocity of a cellular flame normalized by that of a planar flame increased as the pressure became higher and the heat loss became larger. This indicated that the pressure and heat loss affected strongly the unstable motion of cellular-flame fronts. In addition, the fractal dimension became larger, which denoted that the flame shape became more complicated.